2,773 research outputs found

    PRM24 Methods for Analysis of Censored Cost Data

    Get PDF

    Supernova cosmology: legacy and future

    Full text link
    The discovery of dark energy by the first generation of high-redshift supernova surveys has generated enormous interest beyond cosmology and has dramatic implications for fundamental physics. Distance measurements using supernova explosions are the most direct probes of the expansion history of the Universe, making them extremely useful tools to study the cosmic fabric and the properties of gravity at the largest scales. The past decade has seen the confirmation of the original results. Type Ia supernovae are among the leading techniques to obtain high-precision measurements of the dark energy equation of state parameter, and in the near future, its time dependence. The success of these efforts depends on our ability to understand a large number of effects, mostly of astrophysical nature, influencing the observed flux at Earth. The frontier now lies in understanding if the observed phenomenon is due to vacuum energy, albeit its unnatural density, or some exotic new physics. Future surveys will address the systematic effects with improved calibration procedures and provide thousands of supernovae for detailed studies.Comment: Invited review, Annual Review of Nuclear and Particle Science (submitted version

    A Variational Approach for Minimizing Lennard-Jones Energies

    Full text link
    A variational method for computing conformational properties of molecules with Lennard-Jones potentials for the monomer-monomer interactions is presented. The approach is tailored to deal with angular degrees of freedom, {\it rotors}, and consists in the iterative solution of a set of deterministic equations with annealing in temperature. The singular short-distance behaviour of the Lennard-Jones potential is adiabatically switched on in order to obtain stable convergence. As testbeds for the approach two distinct ensembles of molecules are used, characterized by a roughly dense-packed ore a more elongated ground state. For the latter, problems are generated from natural frequencies of occurrence of amino acids and phenomenologically determined potential parameters; they seem to represent less disorder than was previously assumed in synthetic protein studies. For the dense-packed problems in particular, the variational algorithm clearly outperforms a gradient descent method in terms of minimal energies. Although it cannot compete with a careful simulating annealing algorithm, the variational approach requires only a tiny fraction of the computer time. Issues and results when applying the method to polyelectrolytes at a finite temperature are also briefly discussed.Comment: 14 pages, uuencoded compressed postscript fil

    PMH56 A PATIENT PERSPECTIVE ON SIDE EFFECTS OF ANTIPSYCHOTIC THERAPY: THE TOOL INSTRUMENT

    Get PDF

    PMH58 TOOL: MULTI-ATTRIBUTE UTILITY FUNCTION REFLECTING PATIENT EXPERIENCE OF SIDE EFFECTS TO ANTIPSYCHOTIC THERAPY

    Get PDF

    Detailed Abundances for the Old Population near the Galactic Center: I. Metallicity distribution of the Nuclear Star Cluster

    Get PDF
    We report the first high spectral resolution study of 17 M giants kinematically confirmed to lie within a few parsecs of the Galactic Center, using R=24,000 spectroscopy from Keck/NIRSPEC and a new linelist for the infrared K band. We consider their luminosities and kinematics, which classify these stars as members of the older stellar population and the central cluster. We find a median metallicity of =-0.16 and a large spread from approximately -0.3 to +0.3 (quartiles). We find that the highest metallicities are [Fe/H]<+0.6, with most of the stars being at or below the Solar iron abundance. The abundances and the abundance distribution strongly resembles that of the Galactic bulge rather than disk or halo; in our small sample we find no statistical evidence for a dependence of velocity dispersion on metallicity.Comment: 18 pages, 14 figures, accepted for publication in A
    corecore